DC pole | Wartość | Język |
dc.contributor.author | Wojcieszyńska, Danuta | - |
dc.contributor.author | Guzik, Urszula | - |
dc.date.accessioned | 2020-01-23T17:24:56Z | - |
dc.date.available | 2020-01-23T17:24:56Z | - |
dc.date.issued | 2020-01-10 | - |
dc.identifier.citation | Applied Microbiology and Biotechnology, 10 Jan 2020 | pl_PL |
dc.identifier.issn | 0175-7598 | - |
dc.identifier.issn | 1432-0614 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/12195 | - |
dc.description.abstract | This article summarizes the current knowledge about the presence of naproxen in the environment, its toxicity to nontarget
organisms and the microbial degradation of this drug.
Currently, naproxen has been detected in all types of water, including drinking water and groundwater. The concentrations that have
been observed ranged from ng/L to μg/L. These concentrations, although low, may have a negative effect of long-term exposure on
nontarget organisms, especially when naproxen is mixed with other drugs. The biological decomposition of naproxen is performed by
fungi, algae and bacteria, but the only well-described pathway for its complete degradation is the degradation of naproxen by Bacillus
thuringiensis B1(2015b). The key intermediates that appear during the degradation of naproxen by this strain are O-desmethylnaproxen
and salicylate. This latter is then cleaved by 1,2-salicylate dioxygenase or is hydroxylated to gentisate or catechol. These intermediates
can be cleaved by the appropriate dioxygenases, and the resulting products are incorporated into the central metabolism. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/pl/ | * |
dc.subject | Naproxen | pl_PL |
dc.subject | Microorganisms | pl_PL |
dc.subject | Toxicity | pl_PL |
dc.subject | Biodegradation | pl_PL |
dc.title | Naproxen in the environment: its occurrence, toxicity to nontarget organisms and biodegradation | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
dc.identifier.doi | 10.1007/s00253-019-10343-x | - |
Pojawia się w kolekcji: | Artykuły (WNP)
|