Skip navigation

Zastosuj identyfikator do podlinkowania lub zacytowania tej pozycji: http://hdl.handle.net/20.500.12128/138
Tytuł: DNA microarray integromics analysis platform
Autor: Waller, Tomasz
Gubała, Tomasz
Sarapata, Krzysztof
Piwowar, Monika
Jurkowski, Wiktor
Słowa kluczowe: DNA microarray; correlation analysis; DNA microarray analysis Platform
Data wydania: 2015
Źródło: BioData Mining, vol. 8, iss.8 (2015), s. 1-23
Abstrakt: Background: The study of interactions between molecules belonging to different biochemical families (such as lipids and nucleic acids) requires specialized data analysis methods. This article describes the DNA Microarray Integromics Analysis Platform, a unique web application that focuses on computational integration and analysis of "multi-omics" data. Our tool supports a range of complex analyses, including - among others - low- and high-level analyses of DNA microarray data, integrated analysis of transcriptomics and lipidomics data and the ability to infer miRNA-mRNA interactions. Results: We demonstrate the characteristics and benefits of the DNA Microarray Integromics Analysis Platform using two different test cases. The first test case involves the analysis of the nutrimouse dataset, which contains measurements of the expression of genes involved in nutritional problems and the concentrations of hepatic fatty acids. The second test case involves the analysis of miRNA-mRNA interactions in polysaccharide-stimulated human dermal fibroblasts infected with porcine endogenous retroviruses. Conclusions: The DNA Microarray Integromics Analysis Platform is a web-based graphical user interface for "multi-omics" data management and analysis. Its intuitive nature and wide range of available workflows make it an effective tool for molecular biology research. The platform is hosted at https://lifescience.plgrid.pl/
URI: http://hdl.handle.net/20.500.12128/138
DOI: 10.1186/s13040-015-0052-6
ISSN: 1756-0381
Pojawia się w kolekcji:Artykuły (WINOM)

Pliki tej pozycji:
Plik Opis RozmiarFormat 
Waller_DNA microarray integromics analysis platform.pdf2,48 MBAdobe PDFPrzejrzyj / Otwórz
Pokaż pełny rekord


Uznanie Autorstwa 3.0 Polska Creative Commons Creative Commons