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http://hdl.handle.net/20.500.12128/17172| Title: | New insights into the function of mammalian Argonaute2 |
| Authors: | Marzec, Marek |
| Keywords: | MicroRNAs; Crystallization seeding; Nucleotides; Nucleotide sequencing; Binding analysis; Crystal structure; Messenger RNA; RNA structure |
| Issue Date: | 2020 |
| Citation: | "PLOS Genetics" iss. 11 (2020), art. no. e1009058 |
| Abstract: | Uncovering the mechanisms that recognise a microRNA (miRNA) target is 1 of the biggest challenges because the Ago–miRNA complex is able to overcome different derogations of complementarity when binding targets. However, the recently solved crystallographic structure of Argonaute2 (Ago2) and a high-throughput analysis that used repurposed sequencing techniques has brought us closer to achieving this goal. |
| URI: | http://hdl.handle.net/20.500.12128/17172 |
| DOI: | 10.1371/journal.pgen.1009058 |
| ISSN: | 1553-7390 1553-7404 |
| Appears in Collections: | Artykuły (WNP) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Marzec_New_insights_into_the_function_of_mammalian_Argonaute2.pdf | 655,86 kB | Adobe PDF | View/Open |
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