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http://hdl.handle.net/20.500.12128/6379
Tytuł: | Weryfikacja planów leczenia dla urządzenia Gamma Knife za pomocą metod eksperymentalnych stosowanych w fizyce jądrowej |
Autor: | Kokosza, Anna |
Promotor: | Konefał, Adam |
Słowa kluczowe: | radiochirurgia; dozymetria; fizyka jądrowa; Gamma Knife; tomografia; nowotwory; detektory promieniowania |
Data wydania: | 2018 |
Wydawca: | Katowice : Uniwersytet Śląski |
Abstrakt: | The stereotactic radiosurgery is a modern method of treatment of pathological changes in
the head region of a patient, based on a high radiation dose delivered to a target volume during
one fraction. The device used in this type of therapy is the Leksell Gamma Knife Perfexion which
has 192 sources of Co-60 with the solid collimators. It makes it possible to reach a precision better
than 0.05mm.
The purpose of this work was verification of the treatment plans for the therapy by means
of the Leksell Gamma Knife Perfexion device, using the nuclear physics experimental methods.
Two measuring methods were applied i.e. thermoluminescence dosimetry and the method basing
on the dosimetry films. These methods are widely applied in the clinical dosimetry.
Additionally the treatment plans were analyzed with the use of the commercial software
MuCheck called the dose calculator by Data Oncology System. Two dose algorithms: TMR10 and
Convolution available to the treatment planning system were verified. Two original phantoms: the
Film Holder Spherical phantom and the author's modified anthropomorphic phantom provided
with the apparatus were applied. Additionally the absorbed dose measurement was performed
during the computed tomography study, using the TLD method.
The performed verification of plans indicated that there were not any significant
discrepancies between the measured doses and the ones calculated by means of two independent
algorithms of the treatment planning system. The observed differences do not exceed a sum of an
experimental error and a calculation uncertainty.
The main disadvantage of the used methods is relatively long time of the measurements. It
does not make it possible to apply these experimental methods between the prepare of the
treatment plan and the start of the treatment. However they can be used for a spot checks of the
treatment plans, for example, during internal clinical audits. The recalculation of doses by means
of the MuCheck calculating algorithm is enough for verification of the treatment plans for
everyday use. |
URI: | http://hdl.handle.net/20.500.12128/6379 |
Pojawia się w kolekcji: | Rozprawy doktorskie (WNŚiT)
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