Komputerowe wspomaganie gromadzenia i analizy danych z mikromacierzy oligonukleotydowych w badaniach ekspresji genów

Abstract

A relatively new method o f biomedical data acquisition - microarray technology and an example o f computational capacity possibilities for filtering o f microarray data were described. The types o f microarrays used and subsequently microarray experiment steps were discussed. Such kind of experiments makes possible finding changes in gene expression in living cells effected by drugs and other xenobiotics to check the cell resistance or sensibility. Some terms necessary for understanding gene expression and its importance were explained. A proposal o f the data warehouse solution, developed with special attention for storage and the analysis o f microarray data was presented.