DC pole | Wartość | Język |
dc.contributor.author | Metryka, Oliwia | - |
dc.contributor.author | Wasilkowski, Daniel | - |
dc.contributor.author | Nowak, Anna | - |
dc.contributor.author | Adamczyk-Habrajska, Małgorzata | - |
dc.contributor.author | Mrozik, Agnieszka | - |
dc.date.accessioned | 2020-12-01T13:16:42Z | - |
dc.date.available | 2020-12-01T13:16:42Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | "International Journal of Molecular Science" (2020), iss. 23, art. no. 9089, s. 1-18 | pl_PL |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/17480 | - |
dc.description.abstract | Due to the systematic increase in the production of nanomaterials (NMs) and their
applications in many areas of life, issues associated with their toxicity are inevitable. In particular,
the performance of heterogeneous NMs, such as nanocomposites (NCs), is unpredictable as they may
inherit the properties of their individual components. Therefore, the purpose of this work was to
assess the biological activity of newly synthesized Cu/TiO2-NC and the parent nanoparticle substrates
Cu-NPs and TiO2-NPs on the bacterial viability, antioxidant potential and fatty acid composition
of the reference Escherichia coli and Bacillus subtilis strains. Based on the toxicological parameters,
it was found that B. subtilis was more sensitive to NMs than E. coli. Furthermore, Cu/TiO2-NC
and Cu-NPs had an opposite e ect on both strains, while TiO2-NPs had a comparable mode of
action. Simultaneously, the tested strains exhibited varied responses of the antioxidant enzymes
after exposure to the NMs, with Cu-NPs having the strongest impact on their activity. The most
considerable alternations in the fatty acid profiles were found after the bacteria were exposed to
Cu/TiO2-NC and Cu-NPs. Microscopic images indicated distinct interactions of the NMs with the
bacterial outer layers, especially in regard to B. subtilis. Cu/TiO2-NC generally proved to have less
distinctive antimicrobial properties on B. subtilis than E. coli compared to its parent components.
Presumably, the biocidal e ects of the tested NMs can be attributed to the induction of oxidative
stress, the release of metal ions and specific electrochemical interactions with the bacterial cells. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/pl/ | * |
dc.subject | antimicrobial activity | pl_PL |
dc.subject | antioxidant enzymes | pl_PL |
dc.subject | bacteria | pl_PL |
dc.subject | Cu/TiO2 nanocomposite | pl_PL |
dc.subject | Cu and TiO2 nanoparticles | pl_PL |
dc.subject | FAME profiling | pl_PL |
dc.subject | MARA test | pl_PL |
dc.title | Impact of an engineered copper-titanium dioxide nanocomposite and parent substrates on the bacteria viability, antioxidant enzymes and fatty acid profiling | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
dc.identifier.doi | 10.3390/ijms21239089 | - |
Pojawia się w kolekcji: | Artykuły (WNP)
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