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Title: Stenotrophomonas maltophilia : a gram-negative bacterium useful for transformations of flavanone and chalcone
Authors: Kostrzewa-Susłow, Edyta
Dymarska, Monika
Guzik, Urszula
Wojcieszyńska, Danuta
Janeczko, Tomasz
Keywords: flavanone; chalcone; dihydrochalcone; biotransformation; Stenotrophomonas maltophilia
Issue Date: 2018
Citation: Molecules, Vol. 22, Issue 11 (2017), art. no. 1830
Abstract: A group of flavones, isoflavones, flavanones, and chalcones was subjected to small-scale biotransformation studies with the Gram-negative Stenotrophomonas maltophilia KB2 strain in order to evaluate the capability of this strain to transform flavonoid compounds and to investigate the relationship between compound structure and transformation type. The tested strain transformed flavanones and chalcones. The main type of transformation of compounds with a flavanone moiety was central heterocyclic C ring cleavage, leading to chalcone and dihydrochalcone structures, whereas chalcones underwent reduction to dihydrochalcones and cyclisation to a benzo-pyrone moiety. Substrates with a C-2-C-3 double bond (flavones and isoflavones) were not transformed by Stenotrophomonas maltophilia KB2.
DOI: 10.3390/molecules22111830
ISSN: 1420-3049
Appears in Collections:Artykuły (WBiOŚ)

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