Skip navigation

Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12128/9237
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBondarczuk, Kinga-
dc.contributor.authorPiotrowska-Seget, Zofia-
dc.date.accessioned2019-05-29T09:46:48Z-
dc.date.available2019-05-29T09:46:48Z-
dc.date.issued2013-
dc.identifier.citationCell Biology and Toxicology, Vol. 29, iss. 6 (2013), s. 397-405pl_PL
dc.identifier.issn0742-2091-
dc.identifier.urihttp://hdl.handle.net/20.500.12128/9237-
dc.description.abstractCopper is a metallic element that is crucial for cell metabolism; however, in extended concentrations, it is toxic for all living organisms. The dual nature of copper has forced organisms, including bacteria, to keep a tight hold on cellular copper content. This challenge has led to the evolution of complex mechanisms that on one hand enable them to deliver the essential element and on the other to protect cells against its toxicity. Such mechanisms have been found in both eukaryotic and prokaryotic cells. In bacteria a number of different systems such as extra- and intracellular sequestration, enzymatic detoxification, and metal removal from the cell enabling them to survive in the presence of high concentration of copper have been identified. Gram-negative bacteria, due to their additional compartment, need to deal with both cytoplasmic and periplasmic copper. Therefore, these bacteria have evolved intricate and precisely regulated systems which interact with each other. In this review the active mechanisms of copper resistance at their molecular level are discussed.pl_PL
dc.language.isoenpl_PL
dc.rightsUznanie autorstwa 3.0 Polska*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/pl/*
dc.subjectCopApl_PL
dc.subjectcopper resistancepl_PL
dc.subjectCu+-ATPasepl_PL
dc.subjectcuepl_PL
dc.subjectCuePpl_PL
dc.subjectcuspl_PL
dc.subjectMulticopper oxidasepl_PL
dc.subjectpcopl_PL
dc.subjectRNDpl_PL
dc.titleMolecular basis of active cooper resistance mechanisms in Gram-negative bacteriapl_PL
dc.typeinfo:eu-repo/semantics/articlepl_PL
dc.identifier.doi10.1007/s10565-013-9262-1-
Appears in Collections:Artykuły (WNP)

Files in This Item:
File Description SizeFormat 
Bondarczuk_Molecular_basis_of_active_cooper.pdf362,47 kBAdobe PDFView/Open
Show simple item record


Uznanie Autorstwa 3.0 Polska Creative Commons License Creative Commons