http://hdl.handle.net/20.500.12128/9240
Tytuł: | Epigenetic chromatin modifications in barley after mutagenic treatment |
Autor: | Brąszewska-Zalewska, Agnieszka Tylikowska, Marta Kwaśniewska, Jolanta Szymanowska-Pułka, Joanna |
Słowa kluczowe: | Barley; epigenetic modifications; Gamma ray; maleic acid hydrazide; immunostaining; image cytometry |
Data wydania: | 2014 |
Źródło: | Journal of Applied Genetics, Vol. 55, iss. 4 (2014), s. 449-456 |
Abstrakt: | In addition to their normal developmental processes, plants have evolved complex genetic and epigenetic regulatory mechanisms to cope with various environmental stresses. It has been shown that both DNA methylation and histone modifications are involved in DNA damage response to various types of stresses. In this study, we focused on the involvement of two mutagenic agents, chemical (maleic acid hydrazide; MH) and physical (gamma rays), on the global epigenetic modifications of chromatin in barley. Our results indicate that both mutagens strongly influence the level of histone methylation and acetylation. Moreover, we found that gamma irradiation, in contrast to MH, has a more robust influence on the DNA methylation level. This is the first study that brings together mutagenic treatment along with its impact at the level of epigenetic modifications examined using the immunohistochemical method. |
URI: | http://hdl.handle.net/20.500.12128/9240 |
DOI: | 10.1007/s13353-014-0226-9 |
ISSN: | 1234-1983 |
Pojawia się w kolekcji: | Artykuły (WNP) |
Plik | Opis | Rozmiar | Format | |
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Braszewska-Zalewska_Epigenetic_chromatin_modifications.pdf | 4,26 MB | Adobe PDF | Przejrzyj / Otwórz |
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