DC pole | Wartość | Język |
dc.contributor.author | Makieła, Damian | - |
dc.contributor.author | Górny, K. | - |
dc.contributor.author | Gburski, Zygmunt | - |
dc.date.accessioned | 2020-03-23T11:45:17Z | - |
dc.date.available | 2020-03-23T11:45:17Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Acta Physica Polonica A, Vol. 136, iss. 3 (2019), s. 542-547 | pl_PL |
dc.identifier.issn | 0587-4246 | - |
dc.identifier.issn | 1898-794X | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/13222 | - |
dc.description.abstract | Using the molecular dynamics simulation method we studied the aqueous solution ofβ-cyclodextrin and1,2-dimyristoyl-sn-glycero-3phosphocholine (DMPC) molecules. We observed that in water environment DMPCmolecules form a “core” surrounded byβ-cyclodextrins which stick to the surface of DMPC core. The developedβ-cyclodextrin shell (corona) might facilitate the transport of DMPC cluster in bioenvironment. Moreover somesmaller binary complexes, composed of only single pair ofβ-cyclodextrin and DMPC were detected. Our simulationsshowed thatβ-cyclodextrin do not influence the structure of lipid aggregates and should not negatively interferethe liposomal drug delivery systems. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/pl/ | * |
dc.subject | Molecular dynamics | pl_PL |
dc.subject | Phospholipids | pl_PL |
dc.subject | Oligosacharides | pl_PL |
dc.subject | Computer simulation | pl_PL |
dc.title | The effect of β-cyclodextrin on the Formation of Phospholipid Micelles: A Molecular Dynamics Simulation Study | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
dc.identifier.doi | 10.12693/APhysPolA.136.542 | - |
Pojawia się w kolekcji: | Artykuły (WNŚiT)
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