DC pole | Wartość | Język |
dc.contributor.author | Marcoin, Wacława | - |
dc.contributor.author | Duda, Henryk | - |
dc.contributor.author | Chrobak, Dariusz | - |
dc.date.accessioned | 2020-06-26T11:12:28Z | - |
dc.date.available | 2020-06-26T11:12:28Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Polish Journal of Medical Physics and Engineering, 2012, nr 2, s. 55-67 | pl_PL |
dc.identifier.issn | 1898-0309 | - |
dc.identifier.issn | 1425-4689 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/14795 | - |
dc.description.abstract | The paper presents an application of phosphatidylcholine 45% (PC 45) and polyvinylpyrrolidone (PVP) in
formulations of magnesium salts such as Mg(VitB6) and Mg(VitB6Arg) prepared by solid dispersion (SD) techniques.
The evaluation of influence of the selected carriers on some physicochemical properties of solid dispersions and on
the absorption process of Mg +2 ions in vitro were made. An infrared (IR) spectra study suggested creation
of a hydrogen bond between the carriers and the examined magnesium salts. The results of the following thermal
analysis: differential thermal analysis (DTA), thermogravimetry (TG), and differential scanning calorimetry (DSC)
showed that application of PVP into SD lower the temperature of the decomposition process. However, in the case
of PC 45 into SD the characteristic thermal effects of higher temperatures were observed. Moreover, values of the
enthalpy SD of decomposition process were decreased. The results of these studies on absorption process of Mg2+
ions in vitro showed the positive influence of the applied carriers on the partition coefficient values (log P) in the
examined formulation. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/pl/ | * |
dc.subject | Vitamin B6 | pl_PL |
dc.subject | Arginine | pl_PL |
dc.subject | Polyvinylopirrolidone | pl_PL |
dc.subject | Phosphatidylcholine | pl_PL |
dc.subject | Small intestine | pl_PL |
dc.title | Properties of solid dispersions of selected magnesium salts and the absorption process of Mg2+ ions in vitro | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
dc.relation.journal | Polish Journal of Medical Physics and Engineering | pl_PL |
dc.identifier.doi | 10.2478/v10013-011-0006-3 | - |
Pojawia się w kolekcji: | Artykuły (WNŚiT)
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