DC pole | Wartość | Język |
dc.contributor.author | Surma, Robert | - |
dc.contributor.author | Wojcieszyńska, Danuta | - |
dc.contributor.author | Karcz, Jagna | - |
dc.contributor.author | Guzik, Urszula | - |
dc.date.accessioned | 2021-02-12T09:59:14Z | - |
dc.date.available | 2021-02-12T09:59:14Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | "Molecules" (2021), iss. 26, art. no. 820 | pl_PL |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/18996 | - |
dc.description.abstract | Pseudomonas moorei KB4 is capable of degrading paracetamol, but high concentrations
of this drug may cause an accumulation of toxic metabolites. It is known that immobilisation can
have a protective effect on bacterial cells; therefore, the toxicity and degradation rate of paracetamol
by the immobilised strain KB4 were assessed. Strain KB4 was immobilised on a plant sponge. A
toxicity assessment was performed by measuring the concentration of ATP using the colony-forming
unit (CFU) method. The kinetic parameters of paracetamol degradation were estimated using the
Hill equation. Toxicity analysis showed a protective effect of the carrier at low concentrations of
paracetamol. Moreover, a pronounced phenomenon of hormesis was observed in the immobilised
systems. The obtained kinetic parameters and the course of the kinetic curves clearly indicate
a decrease in the degradation activity of cells after their immobilisation. There was a delay in
degradation in the systems with free cells without glucose and immobilised cells with glucose.
However, it was demonstrated that the immobilised systems can degrade at least ten succeeding
cycles of 20 mg/L paracetamol degradation. The obtained results indicate that the immobilised strain
may become a useful tool in the process of paracetamol degradation. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/pl/ | * |
dc.subject | biodegradation | pl_PL |
dc.subject | non-steroidal anti-inflammatory drugs | pl_PL |
dc.subject | immobilisation | pl_PL |
dc.subject | Pseudomonas | pl_PL |
dc.subject | loofah sponge | pl_PL |
dc.subject | paracetamol | pl_PL |
dc.title | Effect of Pseudomonas moorei KB4 Cells’ Immobilisation on Their Degradation Potential and Tolerance towards Paracetamol | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
dc.identifier.doi | 10.3390/molecules26040820 | - |
Pojawia się w kolekcji: | Artykuły (WNŚiT)
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