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http://hdl.handle.net/20.500.12128/22034| Tytuł: | In Vitro Anticancer and Antivirus Activities of Cyano- And Bis (Trifluoromethylsulfonyl) imide-Based Ionic Liquids |
| Autor: | Musiał, Małgorzata Olejniczak, Agnieszka B. Denel-Bobrowska, Marta Zorębski, Edward Dzida, Marzena |
| Słowa kluczowe: | ionic liquids; cytotoxicity; nontumor cells; cancer cells; anticancer activity; antiviral activity |
| Data wydania: | 2021 |
| Źródło: | "ACS Sustainable Chemistry & Engeenering" (2021), Vol. 9, no. 48, art. no. 768347, s. 16459-16465 |
| Abstrakt: | In the current work, we present a broad analysis of cytotoxicity toward normal (kidney and lung) and cancer (lung, liver, and cervix) cells of ionic liquids (ILs) with imidazolium cations and cyano-based or bis(trifluoromethylsulfonyl)imide anions. Additionally, we verify if ILs might be candidates for new potential virucidal agents. We observed the highest biological activity for 1-methyl-3- octylimidazolium bis(trifluoromethylsulfonyl)imide, whereas the least toxic was 1-ethyl-3-methylimidazolium thiocyanate. We found that all investigated ILs revealed a lack of antiviral activity against viruses: human parainfluenza virus type 3 (HPIV-3), human adenovirus 5 (AdV5), human herpesvirus 1 (HSV-1), and human herpesvirus 5 (HCMV) in nontoxic concentrations. |
| URI: | http://hdl.handle.net/20.500.12128/22034 |
| DOI: | 10.1021/acssuschemeng.1c06580 |
| ISSN: | 2168-0485 |
| Pojawia się w kolekcji: | Artykuły (WNŚiT) |
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| Musial_in_vitro_anticancer_and_antivirus.pdf | 2,24 MB | Adobe PDF | Przejrzyj / Otwórz |
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