DC pole | Wartość | Język |
dc.contributor.author | Unni, Aparna Beena | - |
dc.contributor.author | Winkler, Roksana | - |
dc.contributor.author | Marques Duarte, Daniel | - |
dc.contributor.author | Tu, Wenkang | - |
dc.contributor.author | Chat, Katarzyna | - |
dc.contributor.author | Adrjanowicz, Katarzyna | - |
dc.date.accessioned | 2022-05-19T12:41:46Z | - |
dc.date.available | 2022-05-19T12:41:46Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | "The Journal of Physical Chemistry B" (2022), Vol. 0, iss. 0, art. no. 1284 | pl_PL |
dc.identifier.issn | 1520-5207 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/23377 | - |
dc.description.abstract | Crystallization is one of the major challenges in using glassy solids for
technological applications. Considering pharmaceutical drugs, maintaining a stable
amorphous form is highly desirable for improved solubility. Glasses prepared by the
physical vapor deposition technique got attention because they possess very high stability,
taking thousands of years for an ordinary glass to achieve. In this work, we have
investigated the effect of reducing film thickness on the α-relaxation dynamics and
crystallization tendency of vapor-deposited films of celecoxib (CXB), a pharmaceutical
substance. We have scrutinized its crystallization behavior above and below the glasstransition
temperature (Tg). Even though vapor deposition of CXB cannot inhibit
crystallization completely, we found a significant decrease in the crystallization rate with decreasing film thickness. Finally, we have
observed striking differences in relaxation dynamics of vapor-deposited thin films above the Tg compared to spin-coated counterparts
of the same thickness. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/pl/ | * |
dc.subject | Amorphous materials | pl_PL |
dc.subject | Thin films | pl_PL |
dc.subject | Deposition | pl_PL |
dc.subject | Thickness | pl_PL |
dc.subject | Crystallization | pl_PL |
dc.title | Vapor-Deposited Thin Films: Studying Crystallization and α-relaxation Dynamics of the Molecular Drug Celecoxib | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
dc.identifier.doi | 10.1021/acs.jpcb.2c01284 | - |
Pojawia się w kolekcji: | Artykuły (WNŚiT)
|