Skip navigation

Please use this identifier to cite or link to this item:
Title: Synteza bloków budulcowych dla farmacji i chemii metodą katalizy heterogenicznej w układzie nano-Pd/Cu
Authors: Korzec, Mateusz
Advisor: Polański, Jarosław
Keywords: Nanocząstki metali; Pallad związki; Materiały nanokrystaliczne; Kataliza homogeniczna.
Issue Date: 2016
Publisher: Katowice : Uniwersytet Śląski
Abstract: Nanocatalytic system has been investigated in synthesis of selected compounds with potential application in pharmacy and chemistry. The study goal was to determinate the catalytic activity of various bimetallic materials consisting of Pd nanoparticles on the target carriers, such as Ag, AgO, Cu, CuO, Ni. The assays were performed in Sonogashira coupling as a model reaction. This allowed to select the active catalyst, i.e., nanosized palladium particles dispersed on the electrolytic copper (PdNPs/Cu). The method for the preparation of the catalyst and its modification was investigated. In a series of further studies different types of reactions using PdNPs/Cu catalyst were tested. The results that were obtained show high activity of the studied catalyst in the reactions of terminal alkynes with halogen derivatives. The examples of such reactions are: Sonogashira and Cadiota-Chodkiewicz cross coupling and cycloaddition azide-alkyne. In the course of the studies, a potential factors affecting high catalytic activity PdNPs/Cu were identified. Sonogashira coupling products were used for the preparation of the new styrylquinolines which have been described as new group of fluorescent dyes suitable for microscopic imaging of biological structures. The structure of all compound was confirmed by 1H and 13C NMR, ESI-MS analyses, while the purity of a compound was confirmed by: ED-XRF, ICP-MS, HPLC. The obtained catalysts were characterized by means of XPS, TEM, SEM + EDX, XRD.
Description: Praca realizowana w ramach grantu „ORGANOMET” Nr PBS2/A5/40/2014. Autor otrzymał stypendium w ramach projektu DoktoRIS – Program stypendialny na rzecz innowacyjnego Śląska - współfinansowanego przez Unię Europejską w ramach Europejskiego Funduszu Społecznego
Appears in Collections:Rozprawy doktorskie (WNŚiT)

Files in This Item:
File Description SizeFormat 
Korzec_Synteza_blokow_budulcowych_dla_farmacji.pdf13,64 MBAdobe PDFView/Open
Show full item record

Items in RE-BUŚ are protected by copyright, with all rights reserved, unless otherwise indicated.