DC pole | Wartość | Język |
dc.contributor.author | Fulczyk, Agnieszka | - |
dc.contributor.author | Łata, Eliza | - |
dc.contributor.author | Talik, Ewa | - |
dc.contributor.author | Kowalska, Teresa | - |
dc.contributor.author | Sajewicz, Mieczysław | - |
dc.date.accessioned | 2019-04-18T07:46:49Z | - |
dc.date.available | 2019-04-18T07:46:49Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Reaction Kinetics, Mechanisms and Catalysis, Vol. 126 (2019), s. 939–949 | pl_PL |
dc.identifier.issn | 1878-5204 | - |
dc.identifier.issn | 1878-5190 | - |
dc.identifier.issn | 10.1007/s11144-019-01538-4 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12128/8905 | - |
dc.description.abstract | This is our follow-up study carried out in an order to collect experimental evidence
regarding the impact of heavy water (
D2O) on the spontaneous oscillatory peptidization
of the sulfur-containing proteinogenic α-amino acids and this time our target
is l-methionine (l-Met). Our earlier study has been focused on l-cysteine (l-Cys)
and it seemed interesting for us to compare the effect induced by D2O
on these two
structurally related compounds. In a broader sense though, our goal is to investigate
if spontaneous oscillatory peptidization of various different proteinogenic α-amino
acids might play any role in living organisms. As analytical techniques, we used
high-performance liquid chromatography with the evaporative light-scattering
detection (HPLC-ELSD), mass spectrometry (MS), scanning electron microscopy
(SEM), and turbidimetry. The obtained results demonstrate that heavy water seriously
hampers the oscillatory peptidization of l-Met, apparently due to the presence
of the deuterium cation in the reaction medium and in the first instance, due to isotopic
substitution of two functionalities participating in peptidization, i.e., –COOH
and –NH2. This effect is fully analogous to that earlier reported for l-Cys. A cautious
conclusion can be drawn that far more experimental evidence is still needed to
be able to judge about an importance (or otherwise) of the oscillatory peptidization
of proteinogenic α-amino acids for various different life processes. | pl_PL |
dc.language.iso | en | pl_PL |
dc.rights | Uznanie autorstwa 3.0 Polska | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/pl/ | * |
dc.subject | l-Methionine | pl_PL |
dc.subject | D2O | pl_PL |
dc.subject | Spontaneous oscillatory peptidization | pl_PL |
dc.subject | Highperformance liquid chromatography | pl_PL |
dc.subject | Mass spectrometry | pl_PL |
dc.subject | Scanning electron microscopy | pl_PL |
dc.title | Impact of D2O on the peptidization of l‑methionine | pl_PL |
dc.type | info:eu-repo/semantics/article | pl_PL |
Pojawia się w kolekcji: | Artykuły (WNŚiT)
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