http://hdl.handle.net/20.500.12128/18254
Tytuł: | Influence of selected auxiliary substances on some physicochemical properties of solid dispersions containing magnesium salts |
Autor: | Marcoin, Wacława Duda, Henryk |
Słowa kluczowe: | solid dispersion; magnesiurn organie salts |
Data wydania: | 2004 |
Źródło: | "Acta Poloniae Pharmaceutica " 2004, no. 2, s. 97-101 |
Abstrakt: | In this survey magnesium salrn in the form of solid dispersions were studied to examine the interaction of the drug and lecithin or Betain L-7, The results of thermal analysis of solid dispersions containing magnesium adipate Mg[Adip] anJ compounds of this salt with glycine substituent. and the partition coeffident (logP) of this saits applied for solid dispcrsion, have been presented in this paper. Lecithin (45% phosphatidykholine) or Tego" Betain L-7 (30% solution of amide betaine) have been added to magnesium salts to obtain a solid dispersion. The influence of auxiliary substances: Tego" Betain L-7 and lecithin on physicochemkal propcrties of the examined preparations has been assessed. The results of thermal anaiysis ( DT A, DSC, TG) of rnagnesium com pl ex es indicatetl their good thermal res i stance up to the tem,lerature of 375 K. |
URI: | http://hdl.handle.net/20.500.12128/18254 |
ISSN: | 0001-6837 |
Pojawia się w kolekcji: | Artykuły (WNŚiT) |
Plik | Opis | Rozmiar | Format | |
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Marcoin_Influence_of_selected_auxiliary_substances_on_some_physicochemical.pdf | 401,52 kB | Adobe PDF | Przejrzyj / Otwórz |
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