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Zastosuj identyfikator do podlinkowania lub zacytowania tej pozycji: http://hdl.handle.net/20.500.12128/357
Tytuł: KnotProt : a database of proteins with knots and slipknots
Autor: Jamróz, Michał
Niemyska, Wanda
Rawdon, Eric J.
Stasiak, Andrzej
Millett, Kenneth C.
Sułkowski, Piotr
Sułkowska, Joanna
Słowa kluczowe: Knot Prot Database; Protein Conformation; Peptides; Protein Data Bank
Data wydania: 2015
Źródło: Nucleic Acids Research, Vol. 43, iss. D1 (2015), s. D306-D314
Abstrakt: The protein topology database KnotProt, http://knotprot.cent.uw.edu.pl/, collects information about protein structures with open polypeptide chains forming knots or slipknots. The knotting complexity of the cataloged proteins is presented in the form of a matrix diagram that shows users the knot type of the entire polypeptide chain and of each of its subchains. The pattern visible in the matrix gives the knotting fingerprint of a given protein and permits users to determine, for example, the minimal length of the knotted regions (knot's core size) or the depth of a knot, i.e. how many amino acids can be removed from either end of the cataloged protein structure before converting it from a knot to a different type of knot. In addition, the database presents extensive information about the biological functions, families and fold types of proteins with non-trivial knotting. As an additional feature, the KnotProt database enables users to submit protein or polymer chains and generate their knotting fingerprints.
URI: http://hdl.handle.net/20.500.12128/357
DOI: 10.1093/nar/gku1059
ISSN: 0305-1048
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