http://hdl.handle.net/20.500.12128/357
Tytuł: | KnotProt : a database of proteins with knots and slipknots |
Autor: | Jamróz, Michał Niemyska, Wanda Rawdon, Eric J. Stasiak, Andrzej Millett, Kenneth C. Sułkowski, Piotr Sułkowska, Joanna I. |
Słowa kluczowe: | Knot Prot Database; Protein Conformation; Peptides; Protein Data Bank |
Data wydania: | 2015 |
Źródło: | Nucleic Acids Research, Vol. 43, iss. D1 (2015), s. D306-D314 |
Abstrakt: | The protein topology database KnotProt, http://knotprot.cent.uw.edu.pl/, collects information about protein structures with open polypeptide chains forming knots or slipknots. The knotting complexity of the cataloged proteins is presented in the form of a matrix diagram that shows users the knot type of the entire polypeptide chain and of each of its subchains. The pattern visible in the matrix gives the knotting fingerprint of a given protein and permits users to determine, for example, the minimal length of the knotted regions (knot's core size) or the depth of a knot, i.e. how many amino acids can be removed from either end of the cataloged protein structure before converting it from a knot to a different type of knot. In addition, the database presents extensive information about the biological functions, families and fold types of proteins with non-trivial knotting. As an additional feature, the KnotProt database enables users to submit protein or polymer chains and generate their knotting fingerprints. |
URI: | http://hdl.handle.net/20.500.12128/357 |
DOI: | 10.1093/nar/gku1059 |
ISSN: | 0305-1048 |
Pojawia się w kolekcji: | Artykuły (WNŚiT) |
Plik | Opis | Rozmiar | Format | |
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Jamroz_KnotProt_a_database_of_proteins_with_knots_and_slipknots.pdf | 2,02 MB | Adobe PDF | Przejrzyj / Otwórz |
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