Skip navigation

Please use this identifier to cite or link to this item:
Title: Biocompatibility of titania nanotube coatings enriched with silver nanograins by chemical vapor deposition
Authors: Piszczek, P.
Lewandowska, Ż.
Radtke, A.
Jędrzejewski, T.
Kozak, W.
Sadowska, B.
Szubka, Magdalena
Talik, Ewa
Fiori, F.
Keywords: titania nanotube coatings; silver nanograins; surface morphology; biointegration properties; immunological activity
Issue Date: 2017
Citation: Nanomaterials (Basel), Iss. 7 (9), art. no 274 (2017),doi: 10.3390/nano7090274
Abstract: Bioactivity investigations of titania nanotube (TNT) coatings enriched with silver nanograins (TNT/Ag) have been carried out. TNT/Ag nanocomposite materials were produced by combining the electrochemical anodization and chemical vapor deposition methods.Fabricated coatings were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. There lease effect of silver ions from TNT/Ag composites immersedinbodily fluids,has been studied using inductively coupled plasma mass spectrometry (ICP-MS). Themetabolic activity assay (MTT) was applied to determine the L929 murine fibroblasts adhesion and proliferation on the surface of TNT/Ag coatings. Moreover, the results of immunoassays (using peripheral blood mononuclear cells—PBMCs isolated from rats) allowed the estimation of the immunological activity of TNT/Ag surface materials. Antibacterial activity of TNT/Ag coatings with different morphological and structural features was estimated against two Staphylococcus aureus strains (ATCC 29213 and H9). The TNT/Ag nanocomposite layers produced revealed a good biocompatibility promoting the fibroblast adhesion and proliferation. A desirable anti-biofilm activity against the S.aureus reference strain was mainly noticed for these TiO2 nanotube coatings, which contain dispersed Ag nanograins deposited on their surface.
DOI: 10.3390/nano7090274
ISSN: ‎2079-4991
Appears in Collections:Artykuły (WNŚiT)

Files in This Item:
File Description SizeFormat 
Piszczek_Biocompatibility_of_Titania_Nanotube_Coatings_Enriched.pdf3,17 MBAdobe PDFView/Open
Show full item record

Uznanie Autorstwa 3.0 Polska Creative Commons License Creative Commons